Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections.

Okogbenin, Sylvanus; Erameh, Cyril; Okoeguale, Joseph; Edeawe, Osahogie; Ekuaze, Esele; Iraoyah, Kelly; Agho, John; Groger, Mirjam; Kreuels, Benno; Oestereich, Lisa; Babatunde, Femi O; Akhideno, Peter; Günther, Stephan; Ramharter, Michael; Omansen, Till

Okogbenin, Sylvanus; Erameh, Cyril; Okoeguale, Joseph; Edeawe, Osahogie; Ekuaze, Esele; Iraoyah, Kelly; Agho, John; Groger, Mirjam; Kreuels, Benno; Oestereich, Lisa; Babatunde, Femi O; Akhideno, Peter; Günther, Stephan; Ramharter, Michael; Omansen, Till.

Emerg Infect Dis ; 28(10): 2060-2063, 2022 10.

Article em En | MEDLINE | ID: mdl-36148915

ABSTRACT

ABSTRACT

Lassa fever is a viral hemorrhagic fever treated with supportive care and the broad-spectrum antiviral drug ribavirin. The pathophysiology, especially the role of hyperinflammation, of this disease is unknown. We report successful remission of complicated Lassa fever in 2 patients in Nigeria who received the antiinflammatory agent dexamethasone and standard ribavirin.

Assuntos

Febre Lassa; Antivirais/uso terapêutico; Dexametasona/uso terapêutico; Humanos; Febre Lassa/diagnóstico; Febre Lassa/tratamento farmacológico; Vírus Lassa/genética; Ribavirina/uso terapêutico

Palavras-chave

Lassa fever; Lassa mammarenavirus; Lassa virus; Nigeria; concomitant infections; dexamethasone; ribavirin; viral hemorrhagic fever; viruses

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Febre Lassa Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Emerg Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2022 Tipo de documento: Article

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