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Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses.
Mandula, Jessica K; Chang, Shiun; Mohamed, Eslam; Jimenez, Rachel; Sierra-Mondragon, Rosa A; Chang, Darwin C; Obermayer, Alyssa N; Moran-Segura, Carlos M; Das, Satyajit; Vazquez-Martinez, Julio A; Prieto, Karol; Chen, Ann; Smalley, Keiran S M; Czerniecki, Brian; Forsyth, Peter; Koya, Richard C; Ruffell, Brian; Cubillos-Ruiz, Juan R; Munn, David H; Shaw, Timothy I; Conejo-Garcia, Jose R; Rodriguez, Paulo C.
Afiliação
  • Mandula JK; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Chang S; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Mohamed E; California Northstate University, Elk Grove, CA 95757, USA.
  • Jimenez R; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Sierra-Mondragon RA; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Chang DC; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Obermayer AN; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Moran-Segura CM; Department of Pathology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Das S; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Vazquez-Martinez JA; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Prieto K; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Chen A; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Smalley KSM; Department of Tumor Biology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Czerniecki B; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Forsyth P; Department of NeuroOncology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Koya RC; Department of Obstetrics and Gynecology, University of Chicago, Chicago, IL 60637, USA.
  • Ruffell B; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Cubillos-Ruiz JR; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.
  • Munn DH; Department of Pediatrics, Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
  • Shaw TI; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Conejo-Garcia JR; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Rodriguez PC; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA. Electronic address: Paulo.Rodriguez@Moffitt.org.
Cancer Cell ; 40(10): 1145-1160.e9, 2022 10 10.
Article em En | MEDLINE | ID: mdl-36150390
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Interferon Tipo I / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos