Transport dynamics of the hepato-biliary system: a mathematical model allied to Tc 99m IDA scintigraphy.
Phys Med Biol
; 32(6): 719-35, 1987 Jun.
Article
em En
| MEDLINE
| ID: mdl-3615577
ABSTRACT
A generalised mathematical model of hepatic biliary tracer flows is formulated in terms of physiologically identifiable transport parameters. From a particular solution derived from this, the system response to intravenous administration of Tc99m IDA biliary tracer is predicted. Minimisation procedures applied to this solution combined with experimental scintigraphic observations yield estimates for the physiological parameters pertaining to a number of patient studies. Some hepatic conditions where quantitative indicators may contribute to clinical diagnosis are discussed.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Organometálicos
/
Sistema Biliar
/
Compostos de Organotecnécio
/
Iminoácidos
/
Fígado
/
Modelos Biológicos
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Phys Med Biol
Ano de publicação:
1987
Tipo de documento:
Article