From classical mendelian randomization to causal networks for systematic integration of multi-omics.

Yazdani, Azam; Yazdani, Akram; Mendez-Giraldez, Raul; Samiei, Ahmad; Kosorok, Michael R; Schaid, Daniel J

Yazdani, Azam; Yazdani, Akram; Mendez-Giraldez, Raul; Samiei, Ahmad; Kosorok, Michael R; Schaid, Daniel J.

Afiliação

Yazdani A; Center of Perioperative Genetics and Genomics, Brigham Women's Hospital, Harvard Medical School, Boston, MA, United States.
Yazdani A; Health Science Center at Houston, McGovern Medical School, Division of Clinical and Translational Sciences, University of Texas, Houston, TX, United States.
Mendez-Giraldez R; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Samiei A; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, United States.
Kosorok MR; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Schaid DJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.

Front Genet ; 13: 990486, 2022.

Article em En | MEDLINE | ID: mdl-36186433

Palavras-chave

causal networks; classical MR; multiomic integration; principles of mendelian randomization; stability of causal networks; systems approach; systems biology

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Prognostic_studies Idioma: En Revista: Front Genet Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google