What you need to know about: acute liver failure.
Br J Hosp Med (Lond)
; 83(9): 1-11, 2022 Sep 02.
Article
em En
| MEDLINE
| ID: mdl-36193917
ABSTRACT
Acute liver failure is a rare but important clinical syndrome, with a high mortality rate. Prompt recognition, appropriate management and early referral to a liver transplant centre can lead to good outcomes in these critically unwell patients. This article gives an overview of the key clinical challenges and optimal management of patients with acute liver failure. Acute liver failure is defined and a comprehensive list of aetiologies and suggested investigations is provided. The clinical challenges of sepsis, renal impairment, coagulopathy, hypoglycaemia, haemodynamic instability and cerebral oedema are discussed. Quadruple H therapy, a combination of therapies aimed to reduce cerebral oedema in acute liver failure, is described. A systemic guide to managing patients with acute liver failure is provided, as are indications for referral to a liver transplant centre.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Edema Encefálico
/
Transplante de Fígado
/
Falência Hepática Aguda
/
Hipoglicemia
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
Br J Hosp Med (Lond)
Assunto da revista:
HOSPITAIS
/
MEDICINA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Austrália