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Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout.
Steimbach, Raphael R; Herbst-Gervasoni, Corey J; Lechner, Severin; Stewart, Tracy Murray; Klinke, Glynis; Ridinger, Johannes; Géraldy, Magalie N E; Tihanyi, Gergely; Foley, Jackson R; Uhrig, Ulrike; Kuster, Bernhard; Poschet, Gernot; Casero, Robert A; Médard, Guillaume; Oehme, Ina; Christianson, David W; Gunkel, Nikolas; Miller, Aubry K.
Afiliação
  • Steimbach RR; Cancer Drug Development, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Herbst-Gervasoni CJ; Biosciences Faculty, Heidelberg University, 69120 Heidelberg, Germany.
  • Lechner S; Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
  • Stewart TM; Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany.
  • Klinke G; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.
  • Ridinger J; Center for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany.
  • Géraldy MNE; Clinical Cooperation Unit Pediatric Oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Tihanyi G; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120 Heidelberg, Germany.
  • Foley JR; Cancer Drug Development, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Uhrig U; Cancer Drug Development, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Kuster B; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.
  • Poschet G; Chemical Biology Core Facility, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
  • Casero RA; Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany.
  • Médard G; Center for Organismal Studies (COS), Heidelberg University, 69120 Heidelberg, Germany.
  • Oehme I; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.
  • Christianson DW; Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany.
  • Gunkel N; Clinical Cooperation Unit Pediatric Oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
  • Miller AK; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120 Heidelberg, Germany.
J Am Chem Soc ; 144(41): 18861-18875, 2022 10 19.
Article em En | MEDLINE | ID: mdl-36200994
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Histona Desacetilases / Isoenzimas Limite: Humans Idioma: En Revista: J Am Chem Soc Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Histona Desacetilases / Isoenzimas Limite: Humans Idioma: En Revista: J Am Chem Soc Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha