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First-in-Human Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E6742, a Dual Antagonist of Toll-like Receptors 7 and 8, in Healthy Volunteers.
Yamakawa, Naoto; Tago, Fumitoshi; Nakai, Kenya; Kitahara, Yasumi; Ikari, Shingo; Hojo, Seiichiro; Hall, Nancy; Aluri, Jagadeesh; Hussein, Ziad; Gevorkyan, Hakop; Maruyama, Tatsuya; Ishizaka, Sally; Yagi, Takuya.
Afiliação
  • Yamakawa N; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
  • Tago F; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
  • Nakai K; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
  • Kitahara Y; Eisai Inc., Nutley, New Jersey, USA.
  • Ikari S; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
  • Hojo S; Eisai Co., Ltd., Bunkyo-ku, Tokyo, Japan.
  • Hall N; Eisai Inc., Nutley, New Jersey, USA.
  • Aluri J; Eisai Inc., Nutley, New Jersey, USA.
  • Hussein Z; Eisai Ltd., Hatfield, UK.
  • Gevorkyan H; California Clinical Trials Medical Group in affiliation with PAREXEL, Glendale, Glendale, California, USA.
  • Maruyama T; Clinical Research Promotion Center, The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.
  • Ishizaka S; Eisai Inc./Eisai Center for Genetics Guided Dementia Discovery, Cambridge, Massachusetts, USA.
  • Yagi T; Eisai Inc., Nutley, New Jersey, USA.
Clin Pharmacol Drug Dev ; 12(4): 363-375, 2023 04.
Article em En | MEDLINE | ID: mdl-36219471
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Jejum / Receptor 7 Toll-Like Limite: Humans Idioma: En Revista: Clin Pharmacol Drug Dev Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Jejum / Receptor 7 Toll-Like Limite: Humans Idioma: En Revista: Clin Pharmacol Drug Dev Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão