Ganglioside-Functionalized Nanoparticles for Chimeric Antigen Receptor T-Cell Activation at the Immunological Synapse.

Zang, Han; Siddiqui, Menna; Gummuluru, Suryaram; Wong, Wilson W; Reinhard, Björn M

Zang, Han; Siddiqui, Menna; Gummuluru, Suryaram; Wong, Wilson W; Reinhard, Björn M.

Afiliação

Zang H; Departments of Chemistry and The Photonics Center, Boston University, Boston, Massachusetts 02215, United States.
Siddiqui M; Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, Massachusetts 02215, United States.
Gummuluru S; Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts 02118, United States.
Wong WW; Department of Biomedical Engineering and Biological Design Center, Boston University, Boston, Massachusetts 02215, United States.
Reinhard BM; Departments of Chemistry and The Photonics Center, Boston University, Boston, Massachusetts 02215, United States.

ACS Nano ; 16(11): 18408-18420, 2022 11 22.

Article em En | MEDLINE | ID: mdl-36282488

Assuntos

Nanopartículas; Receptores de Antígenos Quiméricos; Receptores de Antígenos Quiméricos/metabolismo; Sinapses Imunológicas/metabolismo; Ligantes; Gangliosídeo G(M3)/metabolismo; Imunoterapia Adotiva; Linfócitos T; Antígenos; Receptores de Antígenos de Linfócitos T

Palavras-chave

CAR T cell activation; Siglec-1/CD169; antigen presenting cell; biomimetic nanomaterials; ganglioside GM3; lipid-coated polymeric nanoparticle

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas / Receptores de Antígenos Quiméricos Idioma: En Revista: ACS Nano Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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