Chitooligosaccharide prevents vascular endothelial cell apoptosis by attenuation of endoplasmic reticulum stress via suppression of oxidative stress through Nrf2-SOD1 up-regulation.

Ei, Zin Zin; Hutamekalin, Pilaiwanwadee; Prommeenate, Peerada; Singh, Avtar; Benjakul, Soottawat; Visuttijai, Kittichate; Chanvorachote, Pithi

Ei, Zin Zin; Hutamekalin, Pilaiwanwadee; Prommeenate, Peerada; Singh, Avtar; Benjakul, Soottawat; Visuttijai, Kittichate; Chanvorachote, Pithi.

Afiliação

Ei ZZ; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.
Hutamekalin P; Division of Health and Applied Sciences, Faculty of Science, Prince of Songkla University, Songkhla, Thailand.
Prommeenate P; Biochemical Engineering and Systems Biology Research Group, National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency at King Mongkut's University of Technology Thonburi, Bangkok, Thailand.
Singh A; International Center of Excellence in Seafood Science and Innovation (ICE-SSI), Faculty of Agro-Industry, Prince of Songkla University, Songkhla, Thailand.
Benjakul S; International Center of Excellence in Seafood Science and Innovation (ICE-SSI), Faculty of Agro-Industry, Prince of Songkla University, Songkhla, Thailand.
Visuttijai K; Department of Laboratory Medicine, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Chanvorachote P; Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

Pharm Biol ; 60(1): 2155-2166, 2022 Dec.

Article em En | MEDLINE | ID: mdl-36300849

Assuntos

Estresse do Retículo Endoplasmático; Fator 2 Relacionado a NF-E2; Fator 2 Relacionado a NF-E2/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Superóxidos/metabolismo; Catalase/metabolismo; Superóxido Dismutase-1/genética; Superóxido Dismutase-1/metabolismo; Superóxido Dismutase-1/farmacologia; Células Endoteliais; Regulação para Cima; Propídio/metabolismo; Propídio/farmacologia; Apoptose; Estresse Oxidativo

Palavras-chave

CHOP; ER stress; ROS; antioxidant; chitosan; shrimp shell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator 2 Relacionado a NF-E2 / Estresse do Retículo Endoplasmático Idioma: En Revista: Pharm Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Tailândia

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