Diffuse pulmonary hemorrhage. An uncommon manifestation of Wegener's granulomatosis.
Am J Surg Pathol
; 11(9): 702-8, 1987 Sep.
Article
em En
| MEDLINE
| ID: mdl-3631383
ABSTRACT
We report two cases of Wegener's granulomatosis with the unusual manifestation of diffuse alveolar hemorrahge. One patient with well-documented Wegener's granulomatosis developed alveolar hemorrhage 4 weeks after leukopenia necessitated the discontinuation of cyclophosphamide. The second patient presented with pulmonary hemorrhage and died 10 days after an open-lung biopsy in which histologic features of Wegener's granulomatosis were overshadowed by alveolar hemorrhage. Lung biopsies in both cases showed marked alveolar hemorrhage and pulmonary capillaritis. The importance of recognizing capillaritis and other subtle histologic features of Wegener's granulomatosis are emphasized.
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Base de dados:
MEDLINE
Assunto principal:
Granulomatose com Poliangiite
/
Hemorragia
/
Pneumopatias
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Am J Surg Pathol
Ano de publicação:
1987
Tipo de documento:
Article