Bupivacaine to Reduce Pain and Narcotic Use After Mohs Micrographic Surgery.
Dermatol Surg
; 48(11): 1135-1139, 2022 11 01.
Article
em En
| MEDLINE
| ID: mdl-36342245
ABSTRACT
BACKGROUND:
Limited data exists for bupivacaine injection after Mohs micrographic surgery (MMS).OBJECTIVE:
Evaluate how bupivacaine affects postoperative pain and narcotic use. MATERIALS ANDMETHODS:
In this multicenter, single-blinded, prospective randomized controlled trial, patients received bupivacaine or saline (placebo) immediately after MMS with flap reconstructions identified by American Academy of Dermatology expert consensus as high-risk for pain and narcotic use. For 48 hours postoperatively, patients logged analgesic use, pain scores (0-10), and whether pain was controlled.RESULTS:
One hundred seventy-four patients were included. Narcotic analgesic use was higher in the placebo group during the first 24 hours (odds ratio 2.18; confidence interval [CI] 1.08-4.41; p = .03), second 24 hours (odds ratio 2.18; CI 0.91-5.29; p = .08), and 48 hours combined (odds ratio 2.58; CI 1.28-5.24; p < .01). Pain scores were lower in the bupivacaine group during the first 8 hours (mean difference 1.6; CI 0.73-2.38; p < .001). Overall analgesic use (narcotic and non-narcotic) and percentage of patients reporting pain under control were similar between groups. There were no significant differences in demographics or surgical characteristics. No adverse events occurred.CONCLUSION:
Single-dose bupivacaine decreased postoperative pain and narcotic analgesic use after MMS with reconstructions likely to cause significant pain. Bupivacaine may have a role in postoperative pain management and reducing narcotic use in this population.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bupivacaína
/
Transtornos Relacionados ao Uso de Opioides
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Dermatol Surg
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article