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Prevalence and risk factors associated with different comorbidities in obese children and adolescents.
López-Galisteo, Juan Pablo; Gavela-Pérez, Teresa; Mejorado-Molano, Francisco Javier; Pérez-Segura, Pilar; Aragón-Gómez, Isabel; Garcés, Carmen; Soriano-Guillén, Leandro.
Afiliação
  • López-Galisteo JP; Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain.
  • Gavela-Pérez T; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
  • Mejorado-Molano FJ; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
  • Pérez-Segura P; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
  • Aragón-Gómez I; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
  • Garcés C; Laboratorio de Lípidos, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain.
  • Soriano-Guillén L; Unidad de Endocrinología Infantil, Servicio de Pediatría, Instituto de Investigación Sanitaria Fundación Jiménez Díaz, Madrid, Spain. Electronic address: leandro.soriano@uam.es.
Endocrinol Diabetes Nutr (Engl Ed) ; 69(8): 566-575, 2022 Oct.
Article em En | MEDLINE | ID: mdl-36347797
INTRODUCTION: Different obesity-related comorbidities already present in childhood, such as: vitamin D deficiency, impaired carbohydrate metabolism, dyslipidaemia, arterial hypertension and non-alcoholic steatohepatitis. In this study, we aim to analyse the prevalence of comorbidities and to determine the predictive factors that affect these comorbidities. MATERIAL AND METHODS: Anthropometric, demographic and biochemical variables were collected from obese patients between six and 18 years of age. Subsequently, a statistical analysis was performed to describe the characteristics of the patients and the prevalence of comorbidities, as well as their predictive factors. RESULTS: A total of 158 obese children (76 boys and 82 girls) with a mean age at diagnosis of 12.48 years and a BMI Z-score of +3.24 SDS were included. The most prevalent comorbidities were vitamin D deficiency (64.2%), insulin resistance (45.1%), dyslipidaemia (32.2%), hyperuricaemia (18.5%) and arterial hypertension (15%). Age, BMI Z-score, percentage of fat mass and male sex have been found to be predictors of these comorbidities. CONCLUSION: Obese children and adolescents have a high prevalence of comorbidities. Once the diagnosis of obesity has been established, it would be very useful to identify early those patients with a higher risk of comorbidities, knowing their relationship with sex, age, BMI Z-score, percentage of fat mass and pubertal stage.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Dislipidemias / Obesidade Infantil / Hipertensão Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Endocrinol Diabetes Nutr (Engl Ed) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina D / Dislipidemias / Obesidade Infantil / Hipertensão Tipo de estudo: Etiology_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Endocrinol Diabetes Nutr (Engl Ed) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Espanha