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Host genetic variability and determinants of severe COVID-19.
Brest, Patrick; Mograbi, Baharia; Gal, Jocelyn; Hofman, Paul; Milano, Gerard.
Afiliação
  • Brest P; Université Côte d'Azur, Institute of Research on Cancer and Aging in Nice (IRCAN), Centre Antoine Lacassagne, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Fédération Hospitalo-Universitaire (FHU) OncoAge, F-06189 Nice, Franc
  • Mograbi B; Université Côte d'Azur, Institute of Research on Cancer and Aging in Nice (IRCAN), Centre Antoine Lacassagne, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Fédération Hospitalo-Universitaire (FHU) OncoAge, F-06189 Nice, Franc
  • Gal J; University Côte d'Azur, Centre Antoine Lacassagne, Epidemiology and Biostatistics Department, 33 avenue de Valombrose, F-06189 Nice, France.
  • Hofman P; Université Côte d'Azur, Institute of Research on Cancer and Aging in Nice (IRCAN), Centre Antoine Lacassagne, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Fédération Hospitalo-Universitaire (FHU) OncoAge, F-06189 Nice, Franc
  • Milano G; Centre Antoine Lacassagne, Service de Valorisation Scientifique, F-06100 Nice, France. Electronic address: gerard.milano@nice.unicancer.fr.
Trends Genet ; 39(3): 169-171, 2023 03.
Article em En | MEDLINE | ID: mdl-36379742
ABSTRACT
Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, convergent studies have provided evidence that host genetic background may contribute to the development of severe coronavirus disease (COVID-19). Here, we summarize how some genetic variations, such as in SARS-CoV-2 receptor angiotensin-converting enzyme 2 or interferon signaling pathway, may help to understand why some individuals can develop severe COVID-19.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Trends Genet Assunto da revista: GENETICA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Revista: Trends Genet Assunto da revista: GENETICA Ano de publicação: 2023 Tipo de documento: Article