A naïve pooled data approach for extrapolation of Phase 0 microdose trials to therapeutic dosing regimens.

van der Heijden, Lisa; van Nuland, Merel; Beijnen, Jos; Huitema, Alwin; Dorlo, Thomas

van der Heijden, Lisa; van Nuland, Merel; Beijnen, Jos; Huitema, Alwin; Dorlo, Thomas.

Afiliação

van der Heijden L; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Nuland M; Division of Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Beijnen J; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Huitema A; Division of Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Dorlo T; Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Clin Transl Sci ; 16(2): 258-268, 2023 02.

Article em En | MEDLINE | ID: mdl-36419385

Assuntos

Desenvolvimento de Medicamentos; Gencitabina; Humanos; Anastrozol; Administração Intravenosa; Protocolos Clínicos; Relação Dose-Resposta a Droga

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenvolvimento de Medicamentos / Gencitabina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Clin Transl Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

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