A year of experience with COVID-19 in patients with cancer: A nationwide study.
Cancer Rep (Hoboken)
; 6(1): e1678, 2023 01.
Article
em En
| MEDLINE
| ID: mdl-36437484
ABSTRACT
BACKGROUND:
Cancer is a major public health problem and comorbidity associated with COVID-19 infection. According to previous studies, a higher mortality rate of COVID-19 in cancer patients has been reported.AIMS:
This study was undertaken to determine associated risk factors and epidemiological characteristics of hospitalized COVID-19 patients with cancer using a nationwide COVID-19 hospital data registry in Iran for the first time.METHODS:
In this retrospective study, we used a national data registry of hospitalized patients with Severe Acute Respiratory Syndrome (SARS) symptoms and patients with confirmed positive COVID-19 PCR between 18 February 2020 and 18 November 2020. The patients were classified into two groups patients with/without malignancy. Logistic regression model was utilized to analyze demographic factors, clinical features, comorbidities, and their associations with the disease outcomes.RESULTS:
In this study, 11 068 and 645 186 in-patients with SARS symptoms with and without malignancy were included, respectively. About 1.11% of our RT-PCR-positive patients had cancer. In patients with malignancy and COVID-19, older ages than 60 (OR 1.88, 95% CI 1.29-2.74, p-value .001), male gender (OR 1.43, 95% CI 1.16-1.77, p-value .001), concomitant chronic pulmonary diseases (CPD) (OR 1.75, 95% CI 1.14-2.68, p-value .009), and presence of dyspnea (OR; 2.00, 95% CI 1.60-2.48, p-value <.001) were associated with increased mortality rate.CONCLUSION:
Given the immunocompromised state of patients with malignancy and their vulnerability to Covid-19 complications, collecting data on the comorbidities and their effects on the disease outcome can build on a better clinical view and help clinicians make decisions to manage these cases better; for example, determining special clinical care, especially in the shortage of health services.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
COVID-19
/
Neoplasias
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
Cancer Rep (Hoboken)
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Irã