<i>In vitro</i> evaluation of the activity of teriflunomide against SARS-CoV-2 and the human coronaviruses 229E and OC43.

Lang, Paul; Geertsen, Svend S; Lublin, Alex L; Potter, Michelle C; Gladysheva, Tatiana; Gregory, Jill S; Rufi, Pascal

In vitro evaluation of the activity of teriflunomide against SARS-CoV-2 and the human coronaviruses 229E and OC43.

Lang, Paul; Geertsen, Svend S; Lublin, Alex L; Potter, Michelle C; Gladysheva, Tatiana; Gregory, Jill S; Rufi, Pascal.

Afiliação

Lang P; Sanofi, 153/211 Second Avenue, Waltham, MA, 02451, USA.
Geertsen SS; Sanofi, 450 Water Street, Cambridge, MA, 02141, USA.
Lublin AL; Sanofi, 450 Water Street, Cambridge, MA, 02141, USA.
Potter MC; Sanofi, 450 Water Street, Cambridge, MA, 02141, USA.
Gladysheva T; Sanofi, 153/211 Second Avenue, Waltham, MA, 02451, USA.
Gregory JS; Sanofi, 153/211 Second Avenue, Waltham, MA, 02451, USA.
Rufi P; Sanofi, 1 Av. Pierre Brossolette, 91380, Chilly-Mazarin, France.

Biochem Biophys Rep ; 33: 101395, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36437966

Palavras-chave

Antiviral; CC50, 50% cytotoxic concentration; COVID-19; COVID-19, coronavirus disease 2019; CPE, cytopathic effect; Coronavirus; EC50, 50% effective concentration; HCoV, human coronavirus; Human cell line; MS, multiple sclerosis; SARS-CoV-2; SARS-CoV-2, severe acute respiratory syndrome coronavirus-2; TCID50, 50% tissue culture infective dose; Teriflunomide; qPCR, quantitative real-time polymerase chain reaction

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Biochem Biophys Rep Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos