SCYL3, as a novel binding partner and regulator of ROCK2, promotes hepatocellular carcinoma progression.
JHEP Rep
; 5(1): 100604, 2023 Jan.
Article
em En
| MEDLINE
| ID: mdl-36440258
CHX, cycloheximide; EV, empty vector; GEO, Gene Expression Omnibus; HCC, hepatocellular carcinoma; HRD motif, histidine-arginine-aspartic acid motif; HTVI, hydrodynamic tail vein injection; Hepatocellular carcinoma; MLC2, myosin light chain 2; Metastasis; NTC, non-target control; OE, overexpression; Protein stability; ROCK2; ROCK2, Rho kinase 2; SB, sleeping beauty; SCYL3; SCYL3 OE, SCYL3-overexpressing; SCYL3, SCY1-like pseudokinase 3; SCYL3-ΔC, SCYL3 mutant with deletion of the C-terminal domain; TCGA, The Cancer Genome Atlas; qPCR, quantitative PCR; sg, single-guide; sh, short-hairpin
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Revista:
JHEP Rep
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Hong Kong