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Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial.
Taylor, Walter R; Olupot-Olupot, Peter; Onyamboko, Marie A; Peerawaranun, Pimnara; Weere, Winifred; Namayanja, Cate; Onyas, Peter; Titin, Harriet; Baseke, Joy; Muhindo, Rita; Kayembe, Daddy K; Ndjowo, Pauline O; Basara, Benjamin B; Bongo, Georgette S; Okalebo, Charles B; Abongo, Grace; Uyoga, Sophie; Williams, Thomas N; Taya, Chiraporn; Dhorda, Mehul; Tarning, Joel; Dondorp, Arjen M; Waithira, Naomi; Fanello, Caterina; Maitland, Kathryn; Mukaka, Mavuto; Day, Nicholas J P.
Afiliação
  • Taylor WR; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: bob@tropmedres.ac.
  • Olupot-Olupot P; Mbale Clinical Research Institute, Mbale, Uganda; Department of Public Health, Busitema University, Mbale, Uganda.
  • Onyamboko MA; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Peerawaranun P; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand.
  • Weere W; Mbale Clinical Research Institute, Mbale, Uganda.
  • Namayanja C; Mbale Clinical Research Institute, Mbale, Uganda.
  • Onyas P; Mbale Clinical Research Institute, Mbale, Uganda.
  • Titin H; Mbale Clinical Research Institute, Mbale, Uganda.
  • Baseke J; Department of Public Health, Busitema University, Mbale, Uganda.
  • Muhindo R; Mbale Clinical Research Institute, Mbale, Uganda.
  • Kayembe DK; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Ndjowo PO; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Basara BB; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Bongo GS; Kinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
  • Okalebo CB; Mbale Clinical Research Institute, Mbale, Uganda.
  • Abongo G; Mbale Clinical Research Institute, Mbale, Uganda.
  • Uyoga S; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
  • Williams TN; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Institute of Global Health Innovation, Imperial College London, London, UK.
  • Taya C; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand.
  • Dhorda M; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Tarning J; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Dondorp AM; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Waithira N; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Fanello C; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Maitland K; KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya; Institute of Global Health Innovation, Imperial College London, London, UK.
  • Mukaka M; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Day NJP; Mahidol Oxford Tropical Medicine Clinical Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Lancet Infect Dis ; 23(4): 471-483, 2023 04.
Article em En | MEDLINE | ID: mdl-36462528
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Deficiência de Glucosefosfato Desidrogenase / Antimaláricos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Child / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: Lancet Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Malária Falciparum / Deficiência de Glucosefosfato Desidrogenase / Antimaláricos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Child / Female / Humans / Infant / Male País/Região como assunto: Africa Idioma: En Revista: Lancet Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2023 Tipo de documento: Article