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High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma.
Grissenberger, Sarah; Sturtzel, Caterina; Wenninger-Weinzierl, Andrea; Radic-Sarikas, Branka; Scheuringer, Eva; Bierbaumer, Lisa; Etienne, Vesnie; Némati, Fariba; Pascoal, Susana; Tötzl, Marcus; Tomazou, Eleni M; Metzelder, Martin; Putz, Eva M; Decaudin, Didier; Delattre, Olivier; Surdez, Didier; Kovar, Heinrich; Halbritter, Florian; Distel, Martin.
Afiliação
  • Grissenberger S; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Sturtzel C; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna, Austria.
  • Wenninger-Weinzierl A; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna, Austria.
  • Radic-Sarikas B; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Department of Pediatric Surgery, Medical University of Vienna, Vienna, Austria.
  • Scheuringer E; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna, Austria.
  • Bierbaumer L; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Etienne V; Laboratory of Preclinical Investigation, Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Némati F; Laboratory of Preclinical Investigation, Department of Translational Research, Institut Curie, PSL University, Paris, France.
  • Pascoal S; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna, Austria.
  • Tötzl M; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Tomazou EM; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Metzelder M; Department of Pediatric Surgery, Medical University of Vienna, Vienna, Austria.
  • Putz EM; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Decaudin D; Laboratory of Preclinical Investigation, Department of Translational Research, Institut Curie, PSL University, Paris, France; Department of Medical Oncology, Institut Curie Research Centre, Paris, France.
  • Delattre O; INSERM U830, Équipe Labellisée LNCC, Diversity and Plasticity of Childhood Tumors Lab, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France.
  • Surdez D; INSERM U830, Équipe Labellisée LNCC, Diversity and Plasticity of Childhood Tumors Lab, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland.
  • Kovar H; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Dept. Pediatrics, Medical University Vienna, Vienna, Austria.
  • Halbritter F; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria.
  • Distel M; St. Anna Children's Cancer Research Institute (CCRI), Vienna, Austria; Zebrafish Platform Austria for Preclinical Drug Screening (ZANDR), Vienna, Austria. Electronic address: martin.distel@ccri.at.
Cancer Lett ; 554: 216028, 2023 02 01.
Article em En | MEDLINE | ID: mdl-36462556
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Áustria
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma de Ewing Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Cancer Lett Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Áustria