Long-term glucocorticoid treatment increases CD204 expression by activating the MAPK pathway and enhances modified LDL uptake in murine macrophages.

Hashimoto, Ryota; Koide, Hiroshi; Katoh, Youichi

Hashimoto, Ryota; Koide, Hiroshi; Katoh, Youichi.

Afiliação

Hashimoto R; Laboratory of Cell Biology, Biomedical Research Core Facilities, Juntendo University Graduate School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan; Department of Physiology, Juntendo University Faculty of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan. Electronic address: hryota@juntendo.ac.jp.
Koide H; Laboratory of Molecular and Biochemical Research, Biomedical Research Core Facilities, Juntendo University Graduate School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan.
Katoh Y; Department of Cardiology, Juntendo University Graduate School of Medicine, Hongo 2-1-1, Bunkyo-ku, Tokyo 113-8421, Japan; Juntendo University Faculty of International Liberal Arts, Hongo 2-1-1, Bunkyo-ku, Tokyo 112-8421, Japan. Electronic address: katoyo@juntendo.ac.jp.

J Pharmacol Sci ; 151(1): 46-53, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36522122

Assuntos

Aterosclerose; Receptores Depuradores Classe A; Camundongos; Animais; Receptores Depuradores Classe A/metabolismo; Glucocorticoides/farmacologia; Lipoproteínas LDL/metabolismo; Macrófagos/metabolismo; Antígenos CD36/genética; Antígenos CD36/metabolismo; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Aterosclerose/tratamento farmacológico; Aterosclerose/metabolismo

Palavras-chave

Atherosclerosis; Glucocorticoids; MAPK pathway; Scavenger receptors; Uptake of modified LDL

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aterosclerose / Receptores Depuradores Classe A Limite: Animals Idioma: En Revista: J Pharmacol Sci Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article

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