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The dual FAK-HDAC inhibitor MY-1259 displays potent activities in gastric cancers in vitro and in vivo.
Song, Jian; Liu, Xu; Zhang, Yi-Fan; Tian, Xin-Yi; Deng, Meng-Yan; Huang, Chen-Zheng; Zhang, Sai-Yang.
Afiliação
  • Song J; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; School of Pharmaceutical Sciences, Institute of Drug Discovery & Development, Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University
  • Liu X; School of Biomedical Sciences, Hunan University, China; School of Pharmaceutical Sciences, Institute of Drug Discovery & Development, Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, Henan 450001, China.
  • Zhang YF; School of Pharmaceutical Sciences, Institute of Drug Discovery & Development, Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University, Zhengzhou, Henan 450001, China.
  • Tian XY; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
  • Deng MY; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
  • Huang CZ; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address: czhuang@zzu.edu.cn.
  • Zhang SY; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China; School of Pharmaceutical Sciences, Institute of Drug Discovery & Development, Key Laboratory of Advanced Drug Preparation Technologies (Ministry of Education), Zhengzhou University
Bioorg Chem ; 131: 106328, 2023 02.
Article em En | MEDLINE | ID: mdl-36542986
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Proteína-Tirosina Quinases de Adesão Focal / Inibidores de Histona Desacetilases / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Gástricas / Proteína-Tirosina Quinases de Adesão Focal / Inibidores de Histona Desacetilases / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article