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The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression.
Corsi, Giulia I; Gadekar, Veerendra P; Haukedal, Henriette; Doncheva, Nadezhda T; Anthon, Christian; Ambardar, Sheetal; Palakodeti, Dasaradhi; Hyttel, Poul; Freude, Kristine; Seemann, Stefan E; Gorodkin, Jan.
Afiliação
  • Corsi GI; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Gadekar VP; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Haukedal H; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Doncheva NT; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark; Novo Nordisk Foundation Center for Protein Research,
  • Anthon C; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Ambardar S; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India; School of Biotechnology, University of Jammu, Jammu and Kashmir 180001, India.
  • Palakodeti D; Institute for Stem Cell Science and Regenerative Medicine, Bangalore 560065, India.
  • Hyttel P; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Freude K; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Seemann SE; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark.
  • Gorodkin J; Center for non-coding RNA in Technology and Health, University of Copenhagen, Frederiksberg 1871, Denmark; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg 1870, Denmark. Electronic address: gorodkin@rth.dk.
Neurobiol Dis ; 178: 105980, 2023 03.
Article em En | MEDLINE | ID: mdl-36572121

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca