Regulatory mechanism of icariin in cardiovascular and neurological diseases.
Biomed Pharmacother
; 158: 114156, 2023 Feb.
Article
em En
| MEDLINE
| ID: mdl-36584431
ABSTRACT
Cardiovascular diseases (CVDs) and neurological diseases are widespread diseases with substantial rates of morbidity and mortality around the world. For the past few years, the preventive effects of Chinese herbal medicine on CVDs and neurological diseases have attracted a great deal of attention. Icariin (ICA), the main constituent of Epimedii Herba, is a flavonoid. It has been shown to provide neuroprotection, anti-tumor, anti-osteoporosis, and cardiovascular protection. The endothelial protection, anti-inflammatory, hypolipidemic, antioxidative stress, and anti-apoptosis properties of ICA can help stop the progression of CVDs and neurological diseases. Therefore, our review summarized the known mechanisms and related studies of ICA in the prevention and treatment of cardio-cerebrovascular diseases (CCVDs), to better understand its therapeutic potential.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Osteoporose
/
Medicamentos de Ervas Chinesas
Limite:
Humans
Idioma:
En
Revista:
Biomed Pharmacother
Ano de publicação:
2023
Tipo de documento:
Article