Investigation of mitochondrial targeting ability of sydnones and sydnonimines and mitochondria-targeted delivery of celecoxib.

Xu, Wenyuan; Yu, Hongzhe; Zhao, Ruohan; Liang, Yong

Xu, Wenyuan; Yu, Hongzhe; Zhao, Ruohan; Liang, Yong.

Afiliação

Xu W; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Yu H; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Zhao R; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Liang Y; State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Chemistry and Biomedicine Innovation Center, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China. Electronic address: yongliang@nju.edu.cn.

Bioorg Med Chem Lett ; 81: 129129, 2023 02 01.

Article em En | MEDLINE | ID: mdl-36634752

Assuntos

Sidnonas; Humanos; Sidnonas/farmacologia; Celecoxib/farmacologia; Mitocôndrias; Células HeLa; Morte Celular

Palavras-chave

Celecoxib; Click-and-release; Mitochondria-targeted; Sydnone; Sydnonimine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sidnonas Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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