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Immune signatures predict development of autoimmune toxicity in patients with cancer treated with immune checkpoint inhibitors.
Nuñez, Nicolas Gonzalo; Berner, Fiamma; Friebel, Ekaterina; Unger, Susanne; Wyss, Nina; Gomez, Julia Martinez; Purde, Mette-Triin; Niederer, Rebekka; Porsch, Maximilian; Lichtensteiger, Christa; Kramer, Rafaela; Erdmann, Michael; Schmitt, Christina; Heinzerling, Lucie; Abdou, Marie-Therese; Karbach, Julia; Schadendorf, Dirk; Zimmer, Lisa; Ugurel, Selma; Klümper, Niklas; Hölzel, Michael; Power, Laura; Kreutmair, Stefanie; Capone, Mariaelena; Madonna, Gabriele; Cevhertas, Lacin; Heider, Anja; Amaral, Teresa; Hasan Ali, Omar; Bomze, David; Dimitriou, Florentia; Diem, Stefan; Ascierto, Paolo Antonio; Dummer, Reinhard; Jäger, Elke; Driessen, Christoph; Levesque, Mitchell Paul; van de Veen, Willem; Joerger, Markus; Früh, Martin; Becher, Burkhard; Flatz, Lukas.
Afiliação
  • Nuñez NG; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Berner F; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland.
  • Friebel E; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Unger S; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Wyss N; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland; Department of Dermatology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Gomez JM; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Purde MT; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland.
  • Niederer R; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland; Department of Dermatology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Porsch M; Department of Radiology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Lichtensteiger C; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland.
  • Kramer R; Department of Dermatology, Uniklinikum Erlangen, Deutsches Zentrum Immuntherapie (DZI), Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nuremberg (CCC ER-EMN), Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany.
  • Erdmann M; Department of Dermatology, Uniklinikum Erlangen, Deutsches Zentrum Immuntherapie (DZI), Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nuremberg (CCC ER-EMN), Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany.
  • Schmitt C; Department of Dermatology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Heinzerling L; Department of Dermatology, Uniklinikum Erlangen, Deutsches Zentrum Immuntherapie (DZI), Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nuremberg (CCC ER-EMN), Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Erlangen, Germany; Department of Dermatology, Ludwig Maximilian
  • Abdou MT; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland.
  • Karbach J; Department of Oncology and Hematology, Krankenhaus Nordwest, Frankfurt, Germany.
  • Schadendorf D; Department of Dermatology, University Hospital Essen and German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany.
  • Zimmer L; Department of Dermatology, University Hospital Essen and German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany.
  • Ugurel S; Department of Dermatology, University Hospital Essen and German Cancer Consortium (DKTK), Partner Site Essen/Düsseldorf, Essen, Germany.
  • Klümper N; Institute for Experimental Oncology, University Hospital Bonn, Bonn, Germany; Center for Integrated Oncology Cologne/Bonn, University Hospital Bonn, Bonn, Germany; Department of Urology, University Hospital Bonn, Bonn, Germany.
  • Hölzel M; Institute for Experimental Oncology, University Hospital Bonn, Bonn, Germany; Center for Integrated Oncology Cologne/Bonn, University Hospital Bonn, Bonn, Germany.
  • Power L; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Kreutmair S; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
  • Capone M; Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Napoli, Italy.
  • Madonna G; Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Napoli, Italy.
  • Cevhertas L; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Department of Medical Immunology, Institute of Health Sciences, Bursa Uludag University, Bursa, Turkey.
  • Heider A; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
  • Amaral T; Skin Cancer Center, Department of Dermatology, University Hospital Tübingen, Tübingen, Germany; iFIT Cluster of Excellence (EXC 2180), University of Tübingen, Tübingen, Germany.
  • Hasan Ali O; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland; Department of Dermatology, Kantonsspital St. Gallen, St. Gallen, Switzerland; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department of Medical
  • Bomze D; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  • Dimitriou F; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Diem S; Department of Medical Oncology and Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Ascierto PA; Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Napoli, Italy.
  • Dummer R; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • Jäger E; Department of Oncology and Hematology, Krankenhaus Nordwest, Frankfurt, Germany.
  • Driessen C; Department of Medical Oncology and Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Levesque MP; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
  • van de Veen W; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
  • Joerger M; Department of Medical Oncology and Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland.
  • Früh M; Department of Medical Oncology and Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland; Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Becher B; Institute of Experimental Immunology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland. Electronic address: becher@immunology.uzh.ch.
  • Flatz L; Institute of Immunobiology, Medical Research Center, Kantonsspital St. Gallen, St.Gallen, Switzerland; Department of Dermatology, Kantonsspital St. Gallen, St. Gallen, Switzerland; Department of Dermatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Department of Medical
Med ; 4(2): 113-129.e7, 2023 02 10.
Article em En | MEDLINE | ID: mdl-36693381
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Doenças do Sistema Imunitário / Neoplasias Pulmonares / Melanoma Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Doenças do Sistema Imunitário / Neoplasias Pulmonares / Melanoma Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça