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Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.
Ganz, Javier; Luquette, Lovelace J; Bizzotto, Sara; Bohrson, Craig L; Jin, Hu; Miller, Michael B; Zhou, Zinan; Galor, Alon; Park, Peter J; Walsh, Christopher A.
Afiliação
  • Ganz J; Division of Genetics and Genomics, Manton Center for Orphan Disease Research, Department of Pediatrics, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
  • Luquette LJ; Departments of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.
  • Bizzotto S; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Bohrson CL; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
  • Jin H; Division of Genetics and Genomics, Manton Center for Orphan Disease Research, Department of Pediatrics, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA.
  • Miller MB; Departments of Pediatrics and Neurology, Harvard Medical School, Boston, MA 02115, USA.
  • Zhou Z; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.
  • Galor A; Sorbonne Université, Institut du Cerveau (Paris Brain Institute) ICM, Inserm, CNRS, Ho pital de la Pitié Salpe triére, Paris, France.
  • Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
  • Walsh CA; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.
bioRxiv ; 2023 Jan 14.
Article em En | MEDLINE | ID: mdl-36711756
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos