Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively.

Raina, Kanak; Forbes, Chris D; Stronk, Rebecca; Rappi, Jonathan P; Eastman, Kyle J; Gerritz, Samuel W; Yu, Xinheng; Li, Hao; Bhardwaj, Amit; Forgione, Mia; Hundt, Abigail; King, Madeline P; Posner, Zoe M; Denny, Allison; McGovern, Andrew; Puleo, David E; Garvin, Ethan; Chenard, Rebekka; Zaware, Nilesh; Mousseau, James J; Macaluso, Jennifer; Martin, Michael; Bassoli, Kyle; Jones, Kelli; Garcia, Marco; Howard, Katia; Smith, Levi M; Chen, Jinshan M; De Leon, Cesar A; Hines, John; Kayser-Bricker, Katherine J; Crews, Craig M

Raina, Kanak; Forbes, Chris D; Stronk, Rebecca; Rappi, Jonathan P; Eastman, Kyle J; Gerritz, Samuel W; Yu, Xinheng; Li, Hao; Bhardwaj, Amit; Forgione, Mia; Hundt, Abigail; King, Madeline P; Posner, Zoe M; Denny, Allison; McGovern, Andrew; Puleo, David E; Garvin, Ethan; Chenard, Rebekka; Zaware, Nilesh; Mousseau, James J; Macaluso, Jennifer; Martin, Michael; Bassoli, Kyle; Jones, Kelli; Garcia, Marco; Howard, Katia; Smith, Levi M; Chen, Jinshan M; De Leon, Cesar A; Hines, John; Kayser-Bricker, Katherine J; Crews, Craig M.

Afiliação

Raina K; co-corresponding authors.
Forbes CD; Halda Therapeutics OpCo Inc, New Haven CT USA.
Stronk R; Halda Therapeutics OpCo Inc, New Haven CT USA.
Rappi JP; Halda Therapeutics OpCo Inc, New Haven CT USA.
Eastman KJ; Halda Therapeutics OpCo Inc, New Haven CT USA.
Gerritz SW; Halda Therapeutics OpCo Inc, New Haven CT USA.
Yu X; Halda Therapeutics OpCo Inc, New Haven CT USA.
Li H; Halda Therapeutics OpCo Inc, New Haven CT USA.
Bhardwaj A; Halda Therapeutics OpCo Inc, New Haven CT USA.
Forgione M; Halda Therapeutics OpCo Inc, New Haven CT USA.
Hundt A; Halda Therapeutics OpCo Inc, New Haven CT USA.
King MP; Halda Therapeutics OpCo Inc, New Haven CT USA.
Posner ZM; Halda Therapeutics OpCo Inc, New Haven CT USA.
Denny A; Halda Therapeutics OpCo Inc, New Haven CT USA.
McGovern A; Halda Therapeutics OpCo Inc, New Haven CT USA.
Puleo DE; Halda Therapeutics OpCo Inc, New Haven CT USA.
Garvin E; Halda Therapeutics OpCo Inc, New Haven CT USA.
Chenard R; Halda Therapeutics OpCo Inc, New Haven CT USA.
Zaware N; Halda Therapeutics OpCo Inc, New Haven CT USA.
Mousseau JJ; Halda Therapeutics OpCo Inc, New Haven CT USA.
Macaluso J; Halda Therapeutics OpCo Inc, New Haven CT USA.
Martin M; Halda Therapeutics OpCo Inc, New Haven CT USA.
Bassoli K; Halda Therapeutics OpCo Inc, New Haven CT USA.
Jones K; Halda Therapeutics OpCo Inc, New Haven CT USA.
Garcia M; Halda Therapeutics OpCo Inc, New Haven CT USA.
Howard K; Halda Therapeutics OpCo Inc, New Haven CT USA.
Smith LM; Halda Therapeutics OpCo Inc, New Haven CT USA.
Chen JM; Halda Therapeutics OpCo Inc, New Haven CT USA.
De Leon CA; Halda Therapeutics OpCo Inc, New Haven CT USA.
Hines J; Department of Molecular, Cellular, & Developmental Biology, Yale University New Haven CT USA.
Kayser-Bricker KJ; Department of Molecular, Cellular, & Developmental Biology, Yale University New Haven CT USA.
Crews CM; Halda Therapeutics OpCo Inc, New Haven CT USA.

bioRxiv ; 2023 Jan 02.

Article em En | MEDLINE | ID: mdl-36711980

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: BioRxiv Ano de publicação: 2023 Tipo de documento: Article