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Structural studies identify angiotensin II receptor blocker-like compounds as branched-chain ketoacid dehydrogenase kinase inhibitors.
Liu, Shenping; Kormos, Bethany L; Knafels, John D; Sahasrabudhe, Parag V; Rosado, Amy; Sommese, Ruth F; Reyes, Allan R; Ward, Jessica; Roth Flach, Rachel J; Wang, Xiaochun; Buzon, Leanne M; Reese, Matthew R; Bhattacharya, Samit K; Omoto, Kiyoyuki; Filipski, Kevin J.
Afiliação
  • Liu S; Medicine Design, Pfizer Inc, Groton, Connecticut, USA. Electronic address: Shenping.liu@pfizer.com.
  • Kormos BL; Medicine Design, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Knafels JD; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Sahasrabudhe PV; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Rosado A; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Sommese RF; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Reyes AR; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Ward J; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Roth Flach RJ; Internal Medicine Research Unit, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Wang X; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Buzon LM; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Reese MR; Medicine Design, Pfizer Inc, Groton, Connecticut, USA.
  • Bhattacharya SK; Medicine Design, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Omoto K; Medicine Design, Pfizer Inc, Cambridge, Massachusetts, USA.
  • Filipski KJ; Medicine Design, Pfizer Inc, Cambridge, Massachusetts, USA. Electronic address: Kevin.Filipski@pfizer.com.
J Biol Chem ; 299(3): 102959, 2023 03.
Article em En | MEDLINE | ID: mdl-36717078
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: 3-Metil-2-Oxobutanoato Desidrogenase (Lipoamida) / Antagonistas de Receptores de Angiotensina Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: 3-Metil-2-Oxobutanoato Desidrogenase (Lipoamida) / Antagonistas de Receptores de Angiotensina Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article