Effects of buprenorphine in heroin addicts.
Drug Alcohol Depend
; 20(1): 1-7, 1987 Sep.
Article
em En
| MEDLINE
| ID: mdl-3678038
ABSTRACT
Twelve heroin addicts on the 8th day after withdrawal, and 8 healthy volunteers were given a single i.m. injection of buprenorphine 0.6 mg and their subjective response rated on 10 psychological variables. Pre-injection rating differed significantly between addicts and controls on 7 variables out of 10. Following buprenorphine more subjective changes were noted in the control group which became more calm, depressed, more aware of the environment, sleepy, tired, intoxicated, dizzy and nauseated. The drug addicts reported changes only in 2 variables (less tense and dysphoric) but otherwise showed no significant changes. These findings support the notion that buprenorphine induces low or normalizing effects in heroin addicts. This drug might thus be suitable for maintenance therapy in opiate addiction.
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Base de dados:
MEDLINE
Assunto principal:
Buprenorfina
/
Dependência de Heroína
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Drug Alcohol Depend
Ano de publicação:
1987
Tipo de documento:
Article
País de afiliação:
Suécia