Apolipoprotein C3 induces inflammasome activation only in its delipidated form.

Hsu, Cheng-Chieh; Shao, Baohai; Kanter, Jenny E; He, Yi; Vaisar, Tomas; Witztum, Joseph L; Snell-Bergeon, Janet; McInnes, Gregory; Bruse, Shannon; Gottesman, Omri; Mullick, Adam E; Bornfeldt, Karin E

Hsu, Cheng-Chieh; Shao, Baohai; Kanter, Jenny E; He, Yi; Vaisar, Tomas; Witztum, Joseph L; Snell-Bergeon, Janet; McInnes, Gregory; Bruse, Shannon; Gottesman, Omri; Mullick, Adam E; Bornfeldt, Karin E.

Afiliação

Hsu CC; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Shao B; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Kanter JE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
He Y; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Vaisar T; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Witztum JL; Department of Medicine, University of California San Diego School of Medicine, La Jolla, CA, USA.
Snell-Bergeon J; Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO, USA.
McInnes G; Empirico Inc, San Diego, CA, USA.
Bruse S; Empirico Inc, San Diego, CA, USA.
Gottesman O; Empirico Inc, San Diego, CA, USA.
Mullick AE; Ionis Pharmaceuticals, Carlsbad, CA, USA.
Bornfeldt KE; Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington Medicine Diabetes Institute, University of Washington, Seattle, WA, USA. kbornfeldt@medicine.washington.edu.

Nat Immunol ; 24(3): 408-411, 2023 03.

Article em En | MEDLINE | ID: mdl-36781985

Assuntos

Inflamassomos; Proteína 3 que Contém Domínio de Pirina da Família NLR; Apolipoproteína C-III

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Proteína 3 que Contém Domínio de Pirina da Família NLR Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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