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Physiologically based pharmacokinetic modeling of tacrolimus for food-drug and CYP3A drug-drug-gene interaction predictions.
Loer, Helena Leonie Hanae; Feick, Denise; Rüdesheim, Simeon; Selzer, Dominik; Schwab, Matthias; Teutonico, Donato; Frechen, Sebastian; van der Lee, Maaike; Moes, Dirk Jan A R; Swen, Jesse J; Lehr, Thorsten.
Afiliação
  • Loer HLH; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
  • Feick D; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
  • Rüdesheim S; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
  • Selzer D; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
  • Schwab M; Clinical Pharmacy, Saarland University, Saarbrücken, Germany.
  • Teutonico D; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany.
  • Frechen S; Departments of Clinical Pharmacology, Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany.
  • van der Lee M; Cluster of Excellence iFIT (EXC2180) "Image-guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany.
  • Moes DJAR; Translational Medicine & Early Development, Sanofi-Aventis Research & Development, Chilly-Mazarin, France.
  • Swen JJ; Bayer AG, Pharmaceuticals, Research & Development, Systems Pharmacology & Medicine, Leverkusen, Germany.
  • Lehr T; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
CPT Pharmacometrics Syst Pharmacol ; 12(5): 724-738, 2023 05.
Article em En | MEDLINE | ID: mdl-36808892
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tacrolimo / Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tacrolimo / Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: CPT Pharmacometrics Syst Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha