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Five New Oleanane Triterpene Saponins from Camellia petelotii and Their Alpha-glucosidase Inhibitory Activity.
Thi Cuc, Nguyen; Anh Bang, Ngo; Huu Tai, Bui; Xuan Nhiem, Nguyen; Hai Yen, Pham; Thi Hai Yen, Duong; Thi Thu Hien, Truong; Thi Huyen, Le; Van Kiem, Phan.
Afiliação
  • Thi Cuc N; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Anh Bang N; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Huu Tai B; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Xuan Nhiem N; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Hai Yen P; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Thi Hai Yen D; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Thi Thu Hien T; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Thi Huyen L; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.
  • Van Kiem P; Center for Toxicology and Radiology Teaching and Research, Vietnam Military Medical University, 160 Phung Hung, Ha Dong, Hanoi, 100000, Vietnam.
Chem Biodivers ; 20(4): e202300093, 2023 Apr.
Article em En | MEDLINE | ID: mdl-36869167
Five new triterpenoid glycosides, named campetelosides A-E (1-5), together with three known compounds, chikusetsusaponin IVa (6), umbellatoside B (7), and silvioside E (8) were isolated from the leaves of Camellia petelotii (Merr.) Sealy. Their chemical structures were determined by interpretations of HR-ESI-MS and NMR spectra. In addition, compounds 1-8 were evaluated for their α-glucosidase inhibitory effects. Compounds 1-3 significantly showed α-glucosidase inhibitory activity with IC50 values of 166.7±6.0, 45.9±2.6, and 395.3±10.5 µM, respectively, compared to that of the positive control, acarbose, with an IC50 value of 200.4±10.5 µM.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Saponinas / Triterpenos / Camellia Idioma: En Revista: Chem Biodivers Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Vietnã
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Oleanólico / Saponinas / Triterpenos / Camellia Idioma: En Revista: Chem Biodivers Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Vietnã