Mapping the Chemical Space of Active-Site Targeted Covalent Ligands for Protein Tyrosine Phosphatases.

Hong, Suk Ho; Xi, Sarah Y; Johns, Andrew C; Tang, Lauren C; Li, Allyson; Hum, Madeleine N; Chartier, Cassandra A; Jovanovic, Marko; Shah, Neel H

Hong, Suk Ho; Xi, Sarah Y; Johns, Andrew C; Tang, Lauren C; Li, Allyson; Hum, Madeleine N; Chartier, Cassandra A; Jovanovic, Marko; Shah, Neel H.

Afiliação

Hong SH; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Xi SY; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Johns AC; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Tang LC; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA.
Li A; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Hum MN; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Chartier CA; Department of Chemistry, Columbia University, New York, NY, 10027, USA.
Jovanovic M; Department of Biological Sciences, Columbia University, New York, NY, 10027, USA.
Shah NH; Department of Chemistry, Columbia University, New York, NY, 10027, USA.

Chembiochem ; 24(10): e202200706, 2023 05 16.

Article em En | MEDLINE | ID: mdl-36893077

Assuntos

Proteínas Tirosina Fosfatases; Tirosina; Domínio Catalítico; Proteínas Tirosina Fosfatases/química; Proteínas Tirosina Fosfatases/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tirosina / Proteínas Tirosina Fosfatases Idioma: En Revista: Chembiochem Assunto da revista: BIOQUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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