Genetic and shared environmental factors explain the association between adolescent polysubstance use and high school noncompletion.
Psychol Addict Behav
; 38(1): 114-123, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-36913302
ABSTRACT
OBJECTIVE:
Examine the nature of the relationship between adolescent polysubstance use and high school noncompletion.METHOD:
Among a sample of 9,579 adult Australian twins (58.63% female, Mage = 30.59), we examined the association between the number of substances used in adolescence and high school noncompletion within a discordant twin design and bivariate twin analysis.RESULTS:
In individual-level models controlling for parental education, conduct disorder symptoms, childhood major depression, sex, zygosity, and cohort, each additional substance used in adolescence was associated with a 30% increase in the odds of high school noncompletion (OR = 1.30 [1.18, 1.42]). Discordant twin models found that the potentially causal effect of adolescent use on high school noncompletion was nonsignificant (OR = 1.19 [0.96, 1.47]). Follow-up bivariate twin models suggested genetic (35.4%, 95% CI [24.5%, 48.7%]) and shared environmental influences (27.8%, 95% CI [12.7%, 35.1%]) each contributed to the covariation in adolescent polysubstance use and early school dropout.CONCLUSIONS:
The association between polysubstance use and early school dropout was largely accounted for by genetic and shared environmental factors, with nonsignificant evidence for a potentially causal association. Future research should examine whether underlying shared risk factors reflect a general propensity for addiction, a broader externalizing liability, or a combination of the two. More evidence using finer measurement of substance use is needed to rule out a causal association between adolescent polysubstance use and high school noncompletion. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Gêmeos
/
Transtorno Depressivo Maior
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
País/Região como assunto:
Oceania
Idioma:
En
Revista:
Psychol Addict Behav
Assunto da revista:
PSICOLOGIA
/
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Ano de publicação:
2024
Tipo de documento:
Article