First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer.

Haughey, Magnus J; Bassolas, Aleix; Sousa, Sandro; Baker, Ann-Marie; Graham, Trevor A; Nicosia, Vincenzo; Huang, Weini

Haughey, Magnus J; Bassolas, Aleix; Sousa, Sandro; Baker, Ann-Marie; Graham, Trevor A; Nicosia, Vincenzo; Huang, Weini.

Afiliação

Haughey MJ; School of Mathematical Sciences, Queen Mary University of London, London, United Kingdom.
Bassolas A; School of Mathematical Sciences, Queen Mary University of London, London, United Kingdom.
Sousa S; School of Mathematical Sciences, Queen Mary University of London, London, United Kingdom.
Baker AM; Centre for Evolution and Cancer, Institute of Cancer Research, London, United Kingdom.
Graham TA; Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Nicosia V; Centre for Evolution and Cancer, Institute of Cancer Research, London, United Kingdom.
Huang W; Centre for Genomics and Computational Biology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

PLoS Comput Biol ; 19(3): e1010952, 2023 03.

Article em En | MEDLINE | ID: mdl-36913406

Assuntos

Evolução Clonal; Neoplasias Colorretais; Humanos; Mutação; Divisão Celular; Neoplasias Colorretais/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Evolução Clonal Limite: Humans Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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