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Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
Gottschlich, Adrian; Thomas, Moritz; Grünmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Müller, Katharina; Xu, Tao; Dhoqina, Dario; Märkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Öykü; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddäus; Lorenzini, Theo; Stock, Sophia; Müller, Philipp Jie; Dörr, Janina; Seifert, Matthias; Cadilha, Bruno L; Brabenec, Ruben; Röder, Natalie; Rataj, Felicitas; Nüesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltrán, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten; Kobold, Sebastian.
Afiliação
  • Gottschlich A; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Thomas M; Bavarian Cancer Research Center (BZKF), Munich, Germany.
  • Grünmeier R; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Lesch S; Institute of AI for Health, Helmholtz Munich, Neuherberg, Germany.
  • Rohrbacher L; School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.
  • Igl V; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Briukhovetska D; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Benmebarek MR; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Vick B; Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany.
  • Dede S; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Müller K; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Xu T; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Dhoqina D; Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Munich, German Research Center for Environmental Health (HMGU), Munich, Germany.
  • Märkl F; Department of Pediatrics, University Hospital, LMU Munich, Munich, Germany.
  • Robinson S; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.
  • Sendelhofert A; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.
  • Schulz H; Department of Neurology, University Hospital, LMU Munich, Munich, Germany.
  • Umut Ö; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Kavaka V; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Tsiverioti CA; Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
  • Carlini E; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Nandi S; Institute of Pathology, LMU Munich, Munich, Germany.
  • Strzalkowski T; Institute of Pathology, LMU Munich, Munich, Germany.
  • Lorenzini T; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Stock S; Institute of Clinical Neuroimmunology, University Hospital, LMU Munich, Munich, Germany.
  • Müller PJ; Biomedical Center (BMC), Faculty of Medicine, LMU Munich, Martinsried, Germany.
  • Dörr J; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Seifert M; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Cadilha BL; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Brabenec R; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Röder N; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Rataj F; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Nüesch M; Department of Medicine III, University Hospital, LMU Munich, Munich, Germany.
  • Modemann F; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.
  • Wellbrock J; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Fiedler W; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Kellner C; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Beltrán E; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Herold T; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Paquet D; Institute of AI for Health, Helmholtz Munich, Neuherberg, Germany.
  • Jeremias I; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • von Baumgarten L; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Endres S; Division of Clinical Pharmacology, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Subklewe M; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Marr C; Mildred Scheel Cancer Career Center, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf Hamburg, Hamburg, Germany.
  • Kobold S; Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nat Biotechnol ; 41(11): 1618-1632, 2023 Nov.
Article em En | MEDLINE | ID: mdl-36914885
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Biotechnol Assunto da revista: BIOTECNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha