The Who, What, When, and Where of Inpatient Direct Oral Penicillin Challenge-Implications for Health Services Implementation.

Trubiano, Jason Anthony; Vogrin, Sara; Mitri, Elise; Hall, Rebecca; Copaescu, Ana; Waldron, Jamie; De Luca, Joseph; Rose, Morgan; Mackay, Geoff; Lambros, Belinda; Douglas, Abby P; Holmes, Natasha E; Chua, Kyra Y L

Trubiano, Jason Anthony; Vogrin, Sara; Mitri, Elise; Hall, Rebecca; Copaescu, Ana; Waldron, Jamie; De Luca, Joseph; Rose, Morgan; Mackay, Geoff; Lambros, Belinda; Douglas, Abby P; Holmes, Natasha E; Chua, Kyra Y L.

Afiliação

Trubiano JA; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Vogrin S; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Mitri E; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Hall R; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Copaescu A; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Waldron J; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
De Luca J; Department of Pharmacy, Austin Health, Heidelberg, Victoria, Australia.
Rose M; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Mackay G; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Lambros B; Department of Infectious Diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Douglas AP; Department of Medicine, Division of Allergy and Clinical Immunology, McGill University Health Center, Montreal, Quebec, Canada.
Holmes NE; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.
Chua KYL; Department of Infectious Diseases, Centre for Antibiotic Allergy and Research, Austin Health, Heidelberg, Victoria, Australia.

Clin Infect Dis ; 77(1): 19-22, 2023 07 05.

Article em En | MEDLINE | ID: mdl-36929823

RESUMO

Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial stewardship initiatives to reduce the burden and impacts of penicillin allergy labels on antibiotic prescribing. Using data from a prospective, multicenter cohort inpatient penicillin allergy program, we identify the key targets for delabeling to aid health service implementation.

Assuntos

Hipersensibilidade a Drogas; Hipersensibilidade; Humanos; Penicilinas/efeitos adversos; Estudos Prospectivos; Pacientes Internados; Antibacterianos/efeitos adversos

Palavras-chave

amoxicillin allergy; antimicrobial stewardship; beta-lactam allergy; drug allergy; oral provocation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipersensibilidade a Drogas / Hipersensibilidade Tipo de estudo: Clinical_trials / Observational_studies Limite: Humans Idioma: En Revista: Clin Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália

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