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A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway.
Yoon, Sae-Bom; Hong, Hyowon; Lim, Hee-Jong; Choi, Ji Hye; Choi, Yoon Pyo; Seo, Seong Wook; Lee, Hyuk Woo; Chae, Chong Hak; Park, Woo-Kyu; Kim, Hyun Young; Jeong, Daeyoung; De, Tran Quang; Myung, Chang-Seon; Cho, Heeyeong.
Afiliação
  • Yoon SB; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Hong H; Department of Pharmacology, Chungnam National University College of Pharmacy, Yuseong-gu, Daejeon 34134, Republic of Korea.
  • Lim HJ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Choi JH; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Choi YP; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Seo SW; Future Medicine Co., Ltd. Rm616 LH-Business Growth Center, Seongnam, Gyeonggido 13449, Republic of Korea.
  • Lee HW; Future Medicine Co., Ltd. Rm616 LH-Business Growth Center, Seongnam, Gyeonggido 13449, Republic of Korea.
  • Chae CH; Future Medicine Co., Ltd. Rm616 LH-Business Growth Center, Seongnam, Gyeonggido 13449, Republic of Korea.
  • Park WK; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Kim HY; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Jeong D; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • De TQ; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Myung CS; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 34114, Republic of Korea.
  • Cho H; Department of Pharmacology, Chungnam National University College of Pharmacy, Yuseong-gu, Daejeon 34134, Republic of Korea.
Acta Pharm Sin B ; 13(3): 1093-1109, 2023 Mar.
Article em En | MEDLINE | ID: mdl-36970199
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Acta Pharm Sin B Ano de publicação: 2023 Tipo de documento: Article