Crocin suppresses breast cancer cell proliferation by down-regulating tumor promoter miR-122-5p and up-regulating tumor suppressors FOXP2 and SPRY2.

Jia, Yunhao; Yang, Han; Yu, Jinsong; Li, Zhong; Jia, Guangwei; Ding, Bo; Lv, Chunliu

Jia, Yunhao; Yang, Han; Yu, Jinsong; Li, Zhong; Jia, Guangwei; Ding, Bo; Lv, Chunliu.

Afiliação

Jia Y; Department of General Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.
Yang H; Department of Endocrinology, Nanshi Hospital Affiliated to Henan University, Nanyang, Henan, 473065, China.
Yu J; Department of Thyroid and Breast Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.
Li Z; Key Laboratory of Thyroid Tumor Prevention and Treatment of Nanyang, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.
Jia G; Department of General Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.
Ding B; Department of Thyroid and Breast Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.
Lv C; Department of General Surgery, Nanyang First People's Hospital Affiliated to Henan University, Nanyang, Henan, 473004, China.

Environ Toxicol ; 38(7): 1597-1608, 2023 Jul.

Article em En | MEDLINE | ID: mdl-36988377

Assuntos

Neoplasias da Mama; MicroRNAs; Humanos; Feminino; MicroRNAs/genética; MicroRNAs/metabolismo; Carcinógenos; Neoplasias da Mama/metabolismo; Linhagem Celular Tumoral; Proliferação de Células/genética; Regulação Neoplásica da Expressão Gênica; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Peptídeos e Proteínas de Sinalização Intracelular/genética; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Fatores de Transcrição Forkhead/genética; Fatores de Transcrição Forkhead/metabolismo

Palavras-chave

FOXP2; SPRY2; breast cancer; crocin; miR-122-5p; proliferation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Environ Toxicol Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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