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Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist.
Karstens, Willem F J; M B P Menge, Wiro; Martens, Gijs; Op Het Veld, Sanne J N; Th H van Eupen, Jacobus; Demon, Marco; van Achterberg, Tanja A E; Arisse-Thijssen, Monica J; Santegoeds-Lenssen, Ellen W H; van der Lee, Miranda M C; Ubink, Ruud; Arends, Roel J; Sesink, Aloys; Blomenröhr, Marion; Marco Timmers, C.
Afiliação
  • Karstens WFJ; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands. Electronic address: willemjan.karstens@byondis.com.
  • M B P Menge W; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Martens G; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Op Het Veld SJN; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Th H van Eupen J; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Demon M; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • van Achterberg TAE; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Arisse-Thijssen MJ; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Santegoeds-Lenssen EWH; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • van der Lee MMC; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Ubink R; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Arends RJ; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Sesink A; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
  • Blomenröhr M; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands; Present address: Bone-Tech BV, Kloosterstraat 9, 5349 AB Oss, The Netherlands.
  • Marco Timmers C; Byondis BV, Microweg 22, 6545 CM Nijmegen, The Netherlands.
Bioorg Med Chem ; 84: 117258, 2023 04 15.
Article em En | MEDLINE | ID: mdl-37001244
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores da Tireotropina / Doença de Graves Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores da Tireotropina / Doença de Graves Limite: Humans Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2023 Tipo de documento: Article