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CD-CODE: crowdsourcing condensate database and encyclopedia.
Rostam, Nadia; Ghosh, Soumyadeep; Chow, Chi Fung Willis; Hadarovich, Anna; Landerer, Cedric; Ghosh, Rajat; Moon, HongKee; Hersemann, Lena; Mitrea, Diana M; Klein, Isaac A; Hyman, Anthony A; Toth-Petroczy, Agnes.
Afiliação
  • Rostam N; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Ghosh S; Center for Systems Biology Dresden, Dresden, Germany.
  • Chow CFW; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Hadarovich A; Center for Systems Biology Dresden, Dresden, Germany.
  • Landerer C; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Ghosh R; Center for Systems Biology Dresden, Dresden, Germany.
  • Moon H; Cluster of Excellence Physics of Life, TU Dresden, Dresden, Germany.
  • Hersemann L; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Mitrea DM; Center for Systems Biology Dresden, Dresden, Germany.
  • Klein IA; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
  • Hyman AA; Center for Systems Biology Dresden, Dresden, Germany.
  • Toth-Petroczy A; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Nat Methods ; 20(5): 673-676, 2023 05.
Article em En | MEDLINE | ID: mdl-37024650
ABSTRACT
The discovery of biomolecular condensates transformed our understanding of intracellular compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about the function and composition of biomolecular condensates, we developed the crowdsourcing condensate database and encyclopedia ( cd-code.org ). CD-CODE is a community-editable platform, which includes a database of biomolecular condensates based on the literature, an encyclopedia of relevant scientific terms and a crowdsourcing web application. Our platform will accelerate the discovery and validation of biomolecular condensates, and facilitate efforts to understand their role in disease and as therapeutic targets.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Crowdsourcing Idioma: En Revista: Nat Methods Assunto da revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Crowdsourcing Idioma: En Revista: Nat Methods Assunto da revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Alemanha