Perforated duodenal ulcer in a dog with gallbladder agenesis.
Open Vet J
; 13(3): 376-381, 2023 03.
Article
em En
| MEDLINE
| ID: mdl-37026077
ABSTRACT
Background:
Duodenal ulceration (DU) in dogs derives from different causes but has never previously been related to gallbladder agenesis (GA). GA is a rare congenital disorder in dogs and is considered a predisposing factor for DU in humans. Case Description A 5-month-old intact female Maltese was presented for acute vomiting and diarrhea. Abdominal ultrasound suggested duodenal perforation and absence of the gallbladder. Exploratory laparotomy was performed to treat the perforation and confirmed GA. Hepatic ductal plate malformation (DPM) was histologically diagnosed in liver biopsy, but no signs of liver dysfunction were detected by blood work at first admission. Two months later, the dog developed signs of portal hypertension and medical treatment was started. However, the clinical condition gradually worsened until liver failure and the dog was euthanized 8 months after surgery. Necropsy confirmed hepatic abnormalities.Conclusion:
This report describes a case of DU associated with GA and DPM in a dog. As in humans, GA may represent a hepatobiliary disease predisposing to gastroduodenal ulcerations.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Úlcera Duodenal
/
Hipertensão Portal
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Female
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Humans
Idioma:
En
Revista:
Open Vet J
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Itália