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Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death.
Woodley, Keith; Dillingh, Laura S; Giotopoulos, George; Madrigal, Pedro; Rattigan, Kevin M; Philippe, Céline; Dembitz, Vilma; Magee, Aoife M S; Asby, Ryan; van de Lagemaat, Louie N; Mapperley, Christopher; James, Sophie C; Prehn, Jochen H M; Tzelepis, Konstantinos; Rouault-Pierre, Kevin; Vassiliou, George S; Kranc, Kamil R; Helgason, G Vignir; Huntly, Brian J P; Gallipoli, Paolo.
Afiliação
  • Woodley K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Dillingh LS; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Giotopoulos G; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Madrigal P; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Rattigan KM; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Philippe C; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Dembitz V; European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, CB10 1SD, UK.
  • Magee AMS; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Asby R; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • van de Lagemaat LN; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Mapperley C; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • James SC; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Prehn JHM; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Tzelepis K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Rouault-Pierre K; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
  • Vassiliou GS; Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland University of Medicine and Health Sciences, Dublin, Ireland.
  • Kranc KR; Wellcome - MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Helgason GV; Department of Haematology, University of Cambridge, Cambridge, UK.
  • Huntly BJP; Milner Therapeutics Institute, University of Cambridge, Cambridge, UK.
  • Gallipoli P; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK.
Nat Commun ; 14(1): 2132, 2023 04 14.
Article em En | MEDLINE | ID: mdl-37059720
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Manose Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Manose Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido