α-D-Glucose as a non-radioactive MRS tracer for metabolic studies of the brain.
Sci Rep
; 13(1): 6159, 2023 04 15.
Article
em En
| MEDLINE
| ID: mdl-37061615
ABSTRACT
Changes in brain glucose metabolism occur in many neurological disorders as well as during aging. Most studies on the uptake of glucose in the brain use positron emission tomography, which requires injection of a radioactive tracer. Our study shows that ultra-high-field 1H-MRS can be used to measure α-D-glucose at 5.22 ppm in vivo, and the α-D-glucose can be used as a radiation-free tracer in the human brain.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Traçadores Radioativos
/
Glucose
Limite:
Humans
Idioma:
En
Revista:
Sci Rep
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Suíça