Boosting stability and therapeutic potential of proteolysis-resistant antimicrobial peptides by end-tagging ß-naphthylalanine.

He, Shiqi; Yang, Zhanyi; Li, Xuefeng; Wu, Hua; Zhang, Licong; Shan, Anshan; Wang, Jiajun

He, Shiqi; Yang, Zhanyi; Li, Xuefeng; Wu, Hua; Zhang, Licong; Shan, Anshan; Wang, Jiajun.

Afiliação

He S; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China.
Yang Z; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China.
Li X; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China.
Wu H; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China.
Zhang L; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China.
Shan A; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China. Electronic address: asshan@neau.edu.cn.
Wang J; Animal Science and Technology College, Northeast Agricultural University, Harbin 150030, PR China. Electronic address: wjj1989@neau.edu.cn.

Acta Biomater ; 164: 175-194, 2023 07 01.

Article em En | MEDLINE | ID: mdl-37100185

Assuntos

Anti-Infecciosos; Peptídeos Antimicrobianos; Proteólise; Peptídeos Catiônicos Antimicrobianos/farmacologia; Peptídeos Catiônicos Antimicrobianos/química; Sais; Anti-Infecciosos/farmacologia; Bactérias; Antibacterianos/farmacologia; Antibacterianos/química; Peptídeo Hidrolases/farmacologia; Aminoácidos; Testes de Sensibilidade Microbiana

Palavras-chave

Anti-proteolytic peptides; Antibacterial mechanism; Antimicrobial stability; End-tagging; Fatty acids; ß-naphthylalanine

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos Antimicrobianos / Anti-Infecciosos Idioma: En Revista: Acta Biomater Ano de publicação: 2023 Tipo de documento: Article

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