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Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Jami, Sina; Deuis, Jennifer R; Klasfauseweh, Tabea; Cheng, Xiaoyang; Kurdyukov, Sergey; Chung, Felicity; Okorokov, Andrei L; Li, Shengnan; Zhang, Jiangtao; Cristofori-Armstrong, Ben; Israel, Mathilde R; Ju, Robert J; Robinson, Samuel D; Zhao, Peng; Ragnarsson, Lotten; Andersson, Åsa; Tran, Poanna; Schendel, Vanessa; McMahon, Kirsten L; Tran, Hue N T; Chin, Yanni K-Y; Zhu, Yifei; Liu, Junyu; Crawford, Theo; Purushothamvasan, Saipriyaa; Habib, Abdella M; Andersson, David A; Rash, Lachlan D; Wood, John N; Zhao, Jing; Stehbens, Samantha J; Mobli, Mehdi; Leffler, Andreas; Jiang, Daohua; Cox, James J; Waxman, Stephen G; Dib-Hajj, Sulayman D; Neely, G Gregory; Durek, Thomas; Vetter, Irina.
Afiliação
  • Jami S; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Deuis JR; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Klasfauseweh T; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Cheng X; Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, USA.
  • Kurdyukov S; Rehabilitation Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Chung F; Dr. John and Anne Chong Lab for Functional Genomics, Charles Perkins Centre, Centenary Institute, University of Sydney, Camperdown, NSW, 2006, Australia.
  • Okorokov AL; Dr. John and Anne Chong Lab for Functional Genomics, Charles Perkins Centre, Centenary Institute, University of Sydney, Camperdown, NSW, 2006, Australia.
  • Li S; Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
  • Zhang J; Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
  • Cristofori-Armstrong B; Institute of Physics, Chinese Academy of Sciences, 100190, Beijing, P.R. China.
  • Israel MR; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Ju RJ; School of Biomedical Sciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Robinson SD; Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE1 1UL, London, UK.
  • Zhao P; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Ragnarsson L; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Andersson Å; Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, USA.
  • Tran P; Rehabilitation Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
  • Schendel V; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • McMahon KL; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Tran HNT; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Chin YK; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Zhu Y; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Liu J; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Crawford T; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Purushothamvasan S; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Habib AM; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Andersson DA; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Rash LD; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Wood JN; College of Medicine, QU Health, Qatar University, PO Box 2713, Doha, Qatar.
  • Zhao J; Wolfson Centre for Age-Related Diseases, Institute of Psychiatry, Psychology & Neuroscience, King's College London, SE1 1UL, London, UK.
  • Stehbens SJ; School of Biomedical Sciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Mobli M; Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
  • Leffler A; Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
  • Jiang D; Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Cox JJ; Centre for Advanced Imaging, The University of Queensland, St Lucia, QLD, 4072, Australia.
  • Waxman SG; Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, 30625, Germany.
  • Dib-Hajj SD; Institute of Physics, Chinese Academy of Sciences, 100190, Beijing, P.R. China.
  • Neely GG; Molecular Nociception Group, Wolfson Institute for Biomedical Research, Division of Medicine, University College London, Gower Street, London, WC1E 6BT, UK.
  • Durek T; Department of Neurology and Center for Neuroscience and Regeneration Research, Yale University School of Medicine, New Haven, CT, USA.
  • Vetter I; Rehabilitation Research Center, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.
Nat Commun ; 14(1): 2442, 2023 04 28.
Article em En | MEDLINE | ID: mdl-37117223
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Biológicas / Urtica dioica Tipo de estudo: Prognostic_studies País/Região como assunto: Oceania Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Biológicas / Urtica dioica Tipo de estudo: Prognostic_studies País/Região como assunto: Oceania Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália