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Position-dependent sequence motif preferences of SpCas9 are largely determined by scaffold-complementary spacer motifs.
Huszár, Krisztina; Welker, Zsombor; Györgypál, Zoltán; Tóth, Eszter; Ligeti, Zoltán; Kulcsár, Péter István; Dancsó, János; Tálas, András; Krausz, Sarah Laura; Varga, Éva; Welker, Ervin.
Afiliação
  • Huszár K; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Welker Z; Department of Genetics, Doctoral School of Biology, Faculty of Science, Eötvös Loránd University, Budapest, H-1117, Hungary.
  • Györgypál Z; Gene Design Ltd, Szeged, Hungary.
  • Tóth E; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Ligeti Z; Biospiral-2006 Ltd, Szeged, Hungary.
  • Kulcsár PI; Biospiral-2006 Ltd, Szeged, Hungary.
  • Dancsó J; Institute of Biophysics, Biological Research Centre, Szeged, Hungary.
  • Tálas A; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Krausz SL; Gene Design Ltd, Szeged, Hungary.
  • Varga É; Institute of Enzymology, Research Centre for Natural Sciences, Budapest, Hungary.
  • Welker E; Institute of Biochemistry, Biological Research Centre, Szeged, Hungary.
Nucleic Acids Res ; 51(11): 5847-5863, 2023 06 23.
Article em En | MEDLINE | ID: mdl-37140059

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptococcus pyogenes / Proteína 9 Associada à CRISPR Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Hungria

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptococcus pyogenes / Proteína 9 Associada à CRISPR Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Hungria