DSPE-PEG polymer enhanced berberine absorption specifically in the small intestine of rats through paracellular passway.

Gao, Yang; Sun, Jianmei; Wang, Shucong; Huxiao, Lisong; Xu, Yali; Zhang, Hailong

Gao, Yang; Sun, Jianmei; Wang, Shucong; Huxiao, Lisong; Xu, Yali; Zhang, Hailong.

Afiliação

Gao Y; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Sun J; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Wang S; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Huxiao L; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Xu Y; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.
Zhang H; School of Pharmacy, Xi'an Jiaotong University, Xi'an, China.

J Pharm Pharmacol ; 75(7): 931-939, 2023 Jul 05.

Article em En | MEDLINE | ID: mdl-37177975

Assuntos

Berberina; Polímeros; Humanos; Ratos; Animais; Polímeros/farmacologia; Berberina/farmacologia; Células CACO-2; Intestino Delgado/metabolismo; Mucosa Intestinal/metabolismo; Absorção Intestinal

Palavras-chave

DSPE-PEG polymer; absorption enhancement; absorption enhancement mechanism; berberine; intestinal absorption

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polímeros / Berberina Limite: Animals / Humans Idioma: En Revista: J Pharm Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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