Axin2-CreERT2 mediated knockout of bone morphogenetic protein receptor type 1A caused abnormal secondary dentine and altered cell fate of Axin2-expressing odontogenic cells.

Xu, Chunmei; Xie, Xudong; Shi, Peilei; Wu, Yafei; Wang, Jun

Xu, Chunmei; Xie, Xudong; Shi, Peilei; Wu, Yafei; Wang, Jun.

Afiliação

Xu C; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China.
Xie X; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China.
Shi P; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China.
Wu Y; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China.
Wang J; State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Periodontics, West China Hospital of Stomatology, Med-X Center for Materials, Sichuan University, Chengdu, China.

Int Endod J ; 56(8): 1000-1010, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37191048

Assuntos

Dentina Secundária; Camundongos; Animais; Microtomografia por Raio-X; Dentina Secundária/metabolismo; Odontogênese; Diferenciação Celular; Odontoblastos; Receptores de Proteínas Morfogenéticas Ósseas/metabolismo; Polpa Dentária; Dentina/patologia; Proteína Axina/metabolismo; Proteína Axina/farmacologia

Palavras-chave

Axin2-expressing cell; bone morphogenetic protein receptor type 1A; odontogenic differentiation; secondary dentin; transgenic mice

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dentina Secundária Limite: Animals Idioma: En Revista: Int Endod J Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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