Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPAR&#945;-NF-&#954;B/IR-S2 signaling pathway.

Reda, Doha; Elshopakey, Gehad E; Albukhari, Talat A; Almehmadi, Samah J; Refaat, Bassem; Risha, Engy F; Mahgoub, Hebatallah A; El-Boshy, Mohamed E; Abdelhamid, Fatma M

Vitamin D3 alleviates nonalcoholic fatty liver disease in rats by inhibiting hepatic oxidative stress and inflammation via the SREBP-1-c/ PPARα-NF-κB/IR-S2 signaling pathway.

Reda, Doha; Elshopakey, Gehad E; Albukhari, Talat A; Almehmadi, Samah J; Refaat, Bassem; Risha, Engy F; Mahgoub, Hebatallah A; El-Boshy, Mohamed E; Abdelhamid, Fatma M.

Afiliação

Reda D; Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Elshopakey GE; Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Albukhari TA; Department of Haematology and Immunology, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia.
Almehmadi SJ; Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Refaat B; Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Risha EF; Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Mahgoub HA; Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
El-Boshy ME; Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Abdelhamid FM; Clinical Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.

Front Pharmacol ; 14: 1164512, 2023.

Article em En | MEDLINE | ID: mdl-37261280

Palavras-chave

hepatic steatosis; high-fat diet; insulin resistance; oxidative stress; vitamin D

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Clinical_trials Idioma: En Revista: Front Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Egito

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